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          2020

  • Googins MR, Woghiren-Afegbua AO, Calderon M, St. Croix CM, Kiselyov KI, VanDemark AP (2020) Structural and functional divergence of GDAP1 from the glutathione S-transferase superfamily. The FASEB Journal volume 34, issue 5

          2019

  • Rosenbaum JC, Bonilla B, Hengel SR, Mertz TM, Herken BW, Kazemier HG, Pressimone CA, Ratterman TC, MacNary E, De Magis A, Kwon Y, Godin SK, Van Houten B, Normolle DP, Sung Patrick, Das SR, Katrin P, Roberts SA, VanDemark AP, Bernstein K. (2019) The Rad51 paralogs facilitate a novel DNA strand specific damage tolerance pathway. Nature communications 10 (1), 1-11.
  • Mikulska-Ruminska K, Shrivastava I, Kreiger J, Zhang S, Li H, Bayir H, Wenzel SE, VanDemark AP, Kagan VE, Bahar I. (2019) Characterization of Differential Dynamics, Specificity, and Allostery of Lipoxygenase Family Members. Journal of chemical information and modeling.
  • Roland BP, Richards KR, Hrizo SL, Eicher S, Barile ZJ, Chang TC, Savon G, Bianchi P, Fermo E, Ricerca BM, Tortorolo L, Vockley J, VanDemark AP, Palladino MJ. (2019) Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease.

          2018

  • Anthonymuthu TS, Kenny EM, Shrivastava IH, Tyurina YY, Hier ZE, Ting HC, Dar HH, Tyurin VA, Nesterova A, Amoscato AA, Mikulska-Ruminska K, Rosenbaum JC, Mao G, Zhao J, Conrad M, Kellum JA, Wenzel SE, VanDemark AP, Bahar I, Kagan VE, Bayir H. (2018) Empowerment of 15-lipoxygenase catalytic competence in selective oxidation of membrane ETE-PE to ferroptotic death signals, HpETE-PE. Journal of the American Chemical Society 140 (51), 17835-17839.

          2017

  • Wenzel SE, Tyurina YY, Zhao J, St.Croiz CM, Dar HH, Mao G, Tyurin VA, Anthonymuthu TS, Kapralov AA, Amoscato AA, Mikulska-Ruminska K, Shrivastava IH, Kenny E, Yang Q, Rosenbaum JC, Sparvero LJ, Emlet DR, Wen X, Minami Y, Qu F, Watkins SC, Holman TR, VanDemark AP, Kellum JA, Bahar I, Bayir H, Kagan VE. (2017) PEBP1 wardens ferroptosis by enabling lipoxygenase generation of lipid death signals. Cell 171 (3), 628-641. e26.
  • Ravi S, VanDemark AP, Kiselyov K. (2017) Regulation of Lysosomal Exocytosis by Oxidative Stress and Calcium Ions. Biophysical Journal 112 (3), 91a.
  • Zalewski JK, Heber S, Mo JH, O'conor K, Hildebrand JD, VanDemark AP. (2017) Combining Wet and Dry Lab Techniques to Guide the Crystallization of Large Coiled-coil Containing Proteins. JoVE (Journal of Visualized Experiments), e54886.

          2016

  • Roland BP, Zeccola AM, Larsen SB, Amrich CG, Talsma AD, Stuchul KA, Heroux A, Levitan ES, VanDemark AP, Palladino MJ. (2016) Structural and genetic studies demonstrate neurologic dysfunction in triosephosphate isomerase deficiency is associated with impaired synaptic vesicle dynamics. PLoS genetics 12 (3), e1005941.
  • Van Oss SB, Shirra MK, Bataille AR, Wier AD, Yen K, Vinayachandran V, Byeon IJL, Cucinotta CE, Heroux A, Jeon J, Kim Jaehoon, VanDemark AP, Pugh BF, Arndt KM. (2016) The histone modification domain of Paf1 complex subunit Rtf1 directly stimulates H2B ubiquitylation through an interaction with Rad6. Environmental & Molecular Mutagenesis.
  • Zalewski JK, Mo JH, Heber S, Heroux A, Gardner RG, Hildebrand JD, VanDemark AP. (2016) Structure of the Shroom-Rho kinase complex reveals a binding interface with monomeric Shroom that regulates cell morphology and stimulates kinase activity. Journal of Biological Chemistry 291 (49), 25364-25374.

          2015

  • Gaines WA, Godin SK, Kabbinavar FF, Rao T, VanDemark AP, Sung P, Bernstein KA (2015) Promotion of presynaptic filament assembly by the ensemble of S. cerevisiae Rad51 paralogues with Rad52. Nature Communications. ePub
  • Roland BP, Amrich CG, Kammerer CJ, Stuchul KA, Larsen SB, Rode S, Aslam AA, Heroux A, Wetzel R, VanDemark AP, Palladino MJ.(2015) Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (1), 61-69.

          2014

  • Roland BP, Amrich CG, Kammerer CJ, Stuchul KA, Larsen SB, Rode S, Aslam AA, Heroux A, Wetzel R, VanDemark AP, Palladino MJ. (2014) Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency. Biochim Biophys Acta. ePub
  • Das D, Zalewski JK, Mohan S, Plageman TF, VanDemark AP, Hildebrand JD. (2014) The interaction between Shroom3 and Rho-kinase is required for neural tube morphogenesis in mice. Biology Open 3, 850-860

          2013

  • Mohan S, Das D, Bauer RJ, Heroux A, Zalewski JK, Heber S, Dosunmu-Ogunbi AM, Trakselis MA, Hildebrand JD, Vandemark AP. (2013) Structure of a Highly Conserved Domain of Rock1 Required for Shroom-Mediated Regulation of Cell Morphology. PLoS One. ePub
  • Singh S, Rockenbach K, Dedrick RM, VanDemark AP, Hatfull GF. (2013) Cross-talk between diverse serine integrases. J Mol Biol. ePub
  • Singh S, Plaks JG, Homa NJ, Amrich CG, Héroux A, Hatfull GF, VanDemark AP. (2013) The Structure of Xis reveals the basis for Filament Formation and insight into DNA bending within a mycobacteriophage Intasome. Journal of Molecular Biology. ePub
  • Wier, A.D., Mayekar, M.K., Heroux, A., Arndt, K.M., VanDemark, A.P. (2013) The structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin. Proc. Natl. Acad. Sci. USA
  • Roland, BP, Stuchul, KA, Larsen, SB, Amrich, CG, VanDemark, AP, Celotto, AM, and Palladino, MJ (2013). Evidence of a triosephosphate isomerase non-catalytic function critical to behavior and longevity. Journal of Cell Science. ePub
  • Godin, S, Wier, A, Kabbinavar, F, Bratton-Palmer, DS, Ghodke, H, Van Houten, B, VanDemark, AP, and Bernstein, KA (2013). The Shu complex interacts with Rad51 through the Rad51 paralogues Rad55-Rad57 to mediate error-free recombination. Nucleic Acids Research 41, 4525-4534

          2012

  • Mohan S, Rizaldy R, Das D, Bauer RJ, Heroux A, Trakselis MA, Hildebrand JD, VanDemark AP (2012) Structure of the Shroom Domain 2 reveals a three-segmented coiled-coil required for dimerization, Rock binding, and apical constriction. Molecular Biology of the Cell 23(11): 2131-2142. PMID: 22493320
  • Amrich CG, Davis CP, Rogal WP, Shirra MK, Heroux A, Gardner RG, Arndt KM, VanDemark AP (2012) Structure of the Cdc73 subunit of the Paf1 complex contains a C-terminal Ras-like domain that promotes association of the Paf1 complex with chromatin. Journal of Biological Chemistry 287(14): 10863-10875. PMID: 22318720

          2010

  • D'Aiuto L, Marzulli M, Mohan KN, Borowczyk E, Saporiti F, VanDemark AP, Chaillet JR (2010) Dissection of structure and function of the N-terminal domain of Mouse DNMT1 using Regional Frame-Shift Mutagenesis. PLoS One 5(3): e9831. PMID: 20352123

          2008

  • VanDemark AP, Xin H, McCullough L, Rawlins R, Bentley S, Heroux A, Stillman, DJ, Hill CP, Formosa T (2008) Structural and Functional Analysis of the Spt16p N-terminal Domain Reveals Overlapping Roles of yFACT Subunits. Journal of Biological Chemistry 283(8): 5058-5068. PMID: 18089575

          2007

  • Welch BD*, VanDemark AP*, Heroux A, Hill CP, Kay MS (2007) Potent D-peptide inhibitors of HIV-1 entry. Proceedings of the National Academy of Sciences of the United States of America 104(43): 16828-16833. PMID: 17942675.
    *Authors contributed equally to this work
  • VanDemark AP, Kasten MM, Ferris E, Heroux A, Hill CP, Cairns BR (2007) Autoregulation of the Rsc4 tandem bromodomain by Gcn5 acetylation. Molecular Cell 27(5): 817-28. PMID: 17803945.

          2006

  • VanDemark AP, Blanksma M, Ferris E, Heroux A, Hill CP, Formosa T (2006) Structure of the yFACT Pob3-M domain, its interaction with the DNA replication factor RPA, and a potential role in histone deposition. Molecular Cell 22(3), 363-374. PMID: 16678108.

          2005

  • Macbeth MR, Shubert HL, VanDemark AP, Lingam AT, Hill CP, Bass BL (2005) Inositol hexakisphosphate is bound in the ADAR2 core and required for RNA editing. Science 309(5740): 1534-1539.
  • VanDemark AP, Hill CP (2005) E1 on the move. Molecular Cell 17(4): 474-475. PMID: 15721250.

          2004

  • VanDemark AP, Hill CP (2004) Grabbing E2 by the tail. Nature Structural & Molecular Biology 11(10): 908-909. PMID: 15452557.

          2003

  • VanDemark AP, Hill CP (2003) Two-stepping with E1. Nature Structural Biology 10(4): 244-246. PMID: 12660720.

          2002

  • VanDemark AP, Hill CP (2002) Structural basis of ubiquitylation. Current Opinion in Structural Biology 12(6): 822-830. PMID: 12504688.
  • VanDemark AP, Hill CP (2002) SUMO wrestling with specificity. Structure 10, 281-282 PMID: 12005425.

          2001

  • VanDemark AP, Hofmann RM, Tsui C, Pickart CM, Wolberger C (2001) Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer. Cell 105(6): 711-720. PMID: 11440714.

          2000

  • Pickart CM, VanDemark AP (2000) Opening doors into the proteasome. Nature Structural Biology 7(11): 999-1001. PMID: 11062549.
  • Jabet C, Sprague ER, VanDemark AP, Wolberger C (2000) Characterization of the N-terminal domain of the yeast transcriptional repressor Tup1. Proposal for an association model of the repressor complex Tup1-Ssn6. Journal of Biological Chemistry 275(12): 9011-9018. PMID: 10722750.

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